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| 发布时间：2007-08-22|
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生物谷报道：美国和意大利的研究人员通过将单个病毒附着在叫做量子点的半导体材料薄片上，制造出一种新型的记忆设备。这种杂交材料能用于开发生物兼容性电子设备，并为制造高密度记忆芯片提供了一种便宜、简单的途径。
一些生物材料能与无机分子相互作用，并且研究人员已经利用这种现象来构建能用作生物传感器的纳米级设备。加州大学河滨分校的Mihri Ozkan和同事制造出一种能够用于储存数字信息的设备，从而向着这个目标前进了一步。
Ozkan和同事首先利用病毒外壳上不同的结合位点将CPMV病毒（cosahedral cowpea mosaic viruses）放在量子点。CPMV是一种对人体无害的植物病毒，直径大约30纳米，由一个外壳和RNA内核构成。
然后，研究人员将这种杂交体包埋进一种聚合物中，并将其夹在两层电极之间进行检测。他们发现每个杂交单元都能够从当一种具有导体特征的记忆设备。这项研究的结果发表在近期的Applied Physics Letters中.
原始出处:
Microscale memory characteristics of virus-quantum dot hybrids
- Nathaniel G. Portney
- Department of Chemical and Environmental Engineering, University of California, Riverside, California 92521
- Ricky J. Tseng
- Department of Materials Science and Engineering, University of California, Los Angeles, California 90095
- Giuseppe Destito
- Department of Cell Biology, Center for Integrative Molecular Biosciences, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037 and Dipartimento di Medicina Sperimentale e Clinica Università degli Studi Magna Graecia di Catanzaro, Viale Europa, Campus Universitario di Germaneto, 88100 Catanzaro, Italy
- Erica Strable
- Department of Chemistry, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037
- Yang Yang
- Department of Materials Science and Engineering, University of California, Los Angeles, California 90095
- Marianne Manchester
- Department of Cell Biology, Center for Integrative Molecular Biosciences, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037
- M. G. Finn
- Department of Chemistry, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037
- Mihrimah Ozkan
- Department of Electrical Engineering, Center for Nanoscale Science and Engineering, University of California, Riverside, California 92521
(Received 7 March 2007; accepted 2 May 2007; published online 23 May 2007)
An electrical multi stability effect was observed for a single layer device fabricated, comprising a hybrid virus-semiconducting quantum dot (CdSe/ZnS core/shell Qds) assembled onto icosahedral-mutant-virus template (CPMV-T184C). A substrate based bottom-up pathway was used to conjugate two different color emitting Qds for fluorescence visualization and to insert a charging/decharging factor. Pulsed wave measurements depicted distinct conductive states with repeatable and nonvolatile behavior as a functioning memory element. ©2007 American Institute of Physics
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美研发“生化飞蛾” 