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| [ 文章来源: | 文章作者:
| 发布时间:2006-09-23|
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声明:仅到2003末为止,2004以后这样的文章更多,大家可以搜索pubmed。
声明:仅到2003末为止,2004以后这样的文章更多,大家可以搜索pubmed。
|
Gene (Ref) |
Accession # |
Position from ATG |
Gene Target (Comments) |
Cell Line Tested |
| ß-actin (1) |
NM_001101 |
972-994 |
aatgaagatcaagatcattgc |
Human HeLa |
| gamma-actin (1) |
NM_001614 |
8-30 |
aagagatcgccgcgctggtca |
Human HeLa |
| AIB1 (estrogen receptor coactivator) (22) |
|
|
AAAGACUCCUUAGGACCGCUU |
Ishikawa |
| Apaf-1 (31) |
|
978-998 |
AATTGGTGCACTTTTACGTGA |
IMR90E1 |
| ARC21 (1) |
AF006086 |
181-203 |
aagaatgaagctgataggacc |
Human HeLa |
| ATR interacting protein (4) |
AF451323 |
254-274 |
AAGGTCCACAGATTATTAGAT |
Human HeLa |
| ATR interacting protein (4) |
AF451323 |
464-484 |
CTAGAGGAACAGAGAAGATCACA |
Human HeLa |
| ATR interacting protein (4) |
AF451323 |
867-887 |
AAGAAGAGGCCCAGAAAAGCT |
Human HeLa |
| Bcr-abl (32) |
|
|
AAGCAGAGUUCAAAAGCCCUU |
TonB, K562, hematopoetic cells |
| Brc-abl (32) |
|
|
AAAGCAGAGUUCAAAAGCCCU |
TonB, K562, hematopoetic cells |
| beta-tubulin- mouse neuronal (21) |
AF312873 |
|
AAGACAGAGCCAAGUGGACUC |
Mouse P19 |
| Bruton's tyrosine kinase (Btk) (33) |
NM_000061 |
1682-1700 |
AAUUGGUAAACGAUCAAGGAG |
RBL-2H3, WEHI-231, NALM-6 |
| Bruton's tyrosine kinase (Btk) (33) |
NM_000061 |
895-913 |
AAGGGAAAGAAGGAGGUUUCA |
RBL-2H3, WEHI-231, NALM-6 |
| Bruton's tyrosine kinase (Btk) (33) |
NM_000061 |
518-536 |
AAGAAGCUUAAAACCUGGGAG |
RBL-2H3, WEHI-231, NALM-6 |
| Casein Kinase I epsilon and delta (CKI-epsilon and CKI-delta) (17) |
|
520-538 |
AACUGGGGAAGAAGGGCAACC |
HEK293 |
| Caspase 1 (34) |
|
191-211 |
AAGGGGCACAGGCATGCCAAA |
IMR90E1A |
| Caspase 2 (34) |
|
94-114 |
AAACAGCTGTTGTTGAGCGAA |
IMR90E1A |
| hCdc2 (24) |
|
125-147 |
|
HeLa |
| Cdc14A (23) |
|
89-109 |
GCACAGTAAATACCCACTATT |
HeLa |
| cdk1 (1) |
NM_001786 |
125-147 |
aaggggttcctagtactgcaa |
Human HeLa |
| CENP-E (1) |
NM_001813 |
944-966 |
aaactcttactgctctccagt |
Human HeLa |
| CHO1 (20) |
|
138-156 |
AAGGUCAGUAAUACAACGGUG |
CHO |
| corin, mouse (12) |
|
|
AACCACCGCCCUCCGUGCA |
HL-5 and 293 |
| Cyclin B1 (5) |
J03166 |
199-217 |
CTCGTACAGCCTTGGGAGACA |
Xenopus embryo |
| Cyclin B2 (5) |
J03167 |
252-270 |
ATGTTAAGACTAAGCATGTAC |
Xenopus embryo |
| cytoplasmic dynein 1 heavy chain (1) |
U53530 |
509-531 |
aaggccaaggaggcgctggaa |
Human HeLa |
| DIP13-alpha (DCC interacting protein) (25) |
|
|
AAGUGCAGCAACACACCUGAC |
DLD1 |
| DIP13-beta (DCC interacting protein) (25) |
|
|
AAGCAGCACCUCUCCUCCCUU |
DLD1 |
Dishevelled (hDv-1 and hDv-3) (16) |
|
|
AACAAGATCACCTTCTCCGAG |
A293 |
hDv-2 (16) |
|
|
AACTTTGAGAACATGAGCAAC |
A293 |
| Eg5 (1) |
NM_004523 |
1547-1569 |
aactggatcgtaagaaggcag |
Human HeLa |
| emerin (1) |
NM_000117 |
628-650 |
aaccgtgctcctggggctggg |
Human HeLa |
| eve (11) |
|
|
AACUCCUUGAACGGCAGCCGC |
Drosophila embryos |
| hFbw7 (cyclin E ubiquitination) (26) |
|
713-735 |
see reference |
HeLa |
| Fortilin (35) |
|
121-141 |
AAGGUAACAUUGAUGACUCGC |
U2OS |
| GalTII (galactosyltransferase II) (27) |
|
65-87 |
AAGCACGCGACGCUGGCGCGC |
HeLa |
| GalTII (galactosyltransferase II) (27) |
|
461-482 |
AAGGCGGACGACGACUCCUUC |
HeLa |
| GAS41 (1) |
NM_006530 |
327-349 |
aagacctgtaaccctgtatca |
Human HeLa |
| Hec-1 (36) |
NM_006101 |
1517-1539 |
|
HeLa-S3 |
| HPV E6 (38) |
|
|
AAGAGGUAUAUGACUUUGCUU |
CaSKi, SiHa, NDF, HCT116 |
| HPV E7 (38) |
|
|
AAAGGAGGAUGAAAUAGAUGG |
CaSKi, SiHa, NDF, HCT116 |
| HtrA2 (28) |
|
|
AAAACGGCUCAGGAUUCGUGG |
U2OS |
| HtrA2 (28) |
|
|
AAGGGGAGTTTGTTGTTGCCA |
U2OS |
| HtrA2 (28) |
|
|
AAGCTTTCCCGATGTTCAGCA |
|
| keratin 18 (1) |
NM_000224 |
1154-1176 |
aagatggcgaggactttaatc |
Human HeLa |
| Kinase interacting stathmin (hKIS) (39) |
|
160-180 |
AAGCAGTTCTTGCCGCCAGGA |
HEK293 |
| Kinase interacting stathmin (mKIS) (39) |
|
160-180 |
AAGCAGTTCCTGCCTCGGGGA |
HEK293 |
| lamin A (13) |
NM019390 |
260-280 |
GAAGCAGCUUCAGGAUGAGAU |
Human HeLa S3 |
| lamin A (19) |
|
|
AAGGACCUGGAGGUCUGCUG |
Hep3B |
| lamin A/C (1) |
NM_005572 |
608-630 |
aactggacttccagaagaaca (90% reduction; 2) |
Human HeLa |
| lamin B1 (1) |
NM_005573 |
672-694 |
aacgcgcttggtagaggtgga |
Human HeLa |
| lamin B2 (1) |
M94362 |
1457-1479 |
aagaggaggaggaagccgagt |
Human HeLa |
| LAP2 (1) |
NM_003276 |
37-59 |
aaagacaagttgaagagtgag |
Human HeLa |
| Mad1 (41) |
AF083811 |
1843-1865 |
See reference |
HeLa-S3 |
| Mammalian septin (MSF) (44) |
AF189712 |
472-492 |
See reference |
HeLa |
Methyl-CpG-binding protein 2 (MeCP2) (19) |
|
|
AAGCAUGAGCCCGUGCAGCCA |
Hep3B |
| Methyl-CpG binding domain protein 2 (MBD2) (19) |
|
|
AAGAGGAUGGAUUGCCCGGCC |
Hep3B |
| Microtubule-associated protein 2 (MAP2) (42) |
|
|
AAUCCUUCGUCUUUCCUCUCG |
primary neuronal cells |
| Myc-induced nuclear antigen 53 (mina53) (40) |
|
45-63 |
See reference |
HeLa, MycB |
| MPS1 kinase (hMps1) (8) |
|
133-155 |
See reference |
Human HeLa S3 |
| Myeloid cell leukemia protein 1 (MCL1) (43) |
|
456-476 |
AACCCGUCCGUACUGGUGUUA |
U2OS |
| Nicastrin (Nct) (45) |
|
|
AAGGGCAAGTTTCCCGTGCAG |
HEK293 |
| NuMA (1) |
Z11583 |
3988-4010 |
aaggcgtggcaggagaagttc |
Human HeLa |
| Nup153 (1) |
NM_005124 |
2593-2615 |
aaggcagactctaccaaatgt |
Human HeLa |
| Origin recognition complex protein 6 (Orc6) (46) |
|
|
AAUGGUAGCCACAUCCGGUGU |
HeLa |
| Origin recognition complex protein 6 (Orc6) (46) |
|
|
AAGATTGGACAGCAGGUCGAC |
HeLa |
| P160 ROCK (47) |
|
566-584; 639-657; 1958-1976; 2780-2798 |
See reference |
|
| Polo-like Kinase1 (hPlk1) (37) |
NM_005030 |
181-203 |
AAGGGCGGCTTTGCCAAGTGC |
HeLa, U2OS |
| Protein Kinase Receptor (PKR) (9) |
|
931-949 |
AAGATCAAGTTTTGCCAATG |
Human HeLa |
| hRad9 (29) |
U53174 |
232-252 |
AAGUCUUUCCUGUCUGUCUUU |
MCF-7 |
| Rad17 (7) |
|
|
AACAGACUGGGUUGACCCAUC |
Human HeLa |
| Signalling Adapter/scaffold protein (h/m Shc) (3) |
HSU73377 |
677-697 |
tcctacttggttcggtacatggg |
Human HeLa |
| p66 ShcA (3) |
HSU73377 |
236-256 |
CGGAATGAGTCTCTGTCATCGTC |
Human HeLa |
Sphingosine kinase 1 (hSK1) (15) |
|
70 nt downstream of start codon |
AAGAGCUGCAAGGCCUUGCCC |
HUVEC |
| Steroid receptor coactivator (SRC-1) (30) |
|
|
CCUCAGGGCAGAGAACCAUCUTT |
Ishikawa |
| ß-tubulin (6) |
AF312873 |
3'-UTR |
GACAGAGCCAAGUGGACUCAC |
Mouse P19 |
| Tissue Factor (hTF) (18) |
M16553 |
|
AAGCGCUUCAGGCACUACAAA |
HeLa, 293, Cos-1, HaCaT |
| Tissue Factor (hTF) (18) |
M16553 |
|
AAGAAGCAGACGUACUUGGCA |
HeLa, 293, Cos-1, HaCaT |
| ß-transducin repeat-containing protein (ß-TrCP), human (10) |
|
|
GUGGAAUUUGUGGAACAUCTT |
293 |
| TSG101 (a ubiquitin enzyme 2 variant protein) (14) |
|
413-433 |
AACCUCCAGUCUUCUCUCGUC |
Human HeLa-M & HeLa KK3 |
| VASP (1) |
XM_009141 |
1087-1109 |
aaagaggaaatcattgaagcc |
Human HeLa |
| vimentin (1) |
NM_003380 |
346-368 |
aactacatcgacaaggtgcgc (No silencing observed; 1,2) |
Human HeLa |
| vimentin (1) |
NM_003380 |
1145-1167 |
aataccaagacctgctcaatg |
Human HeLa |
| vimentin (1) |
NM_003380 |
863-885 |
aagaatggtacaaatccaagt |
Human HeLa |
| vimentin (1) |
NM_003380 |
1037-1059 |
aaatggaagagaactttgccg |
Human HeLa |
| vinculin, mouse (1) |
L18880 |
2923-2945 |
aagcggattagaaccaatctc |
Mouse 3T3 |
| zyxin, mouse (1) |
X99063 |
1357-1379 |
aaagcctaccacccacagtgc |
Mouse 3T3 |
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